What is Global Longitudinal Strain?
GLS detects early changes in cardiac function before they become visible with conventional measurements — and before symptoms appear. This means action can be taken earlier to prevent irreversible damage.
The GE Vivid E95 system used in our clinic is an internationally recognised standard for this examination. It precisely identifies which segment of the myocardium is affected — a critical piece of information for accurate diagnosis and treatment decisions.
GLS is performed alongside the heart triplex, with no additional preparation required. D. Boukis evaluates the findings within the overall clinical picture and issues a report with specific, individualised recommendations.
Why is it important?
- Subclinical dysfunction detection
- Early cardiotoxicity indicator
- High prognostic value

GLS with GE Vivid E95: Detection Before Symptoms
GLS detects early changes in cardiac function before they become visible with conventional measurements — and before symptoms appear. This means action can be taken earlier to prevent irreversible damage.
The GE Vivid E95 system used in our clinic is an internationally recognised standard for this examination. It precisely identifies which segment of the myocardium is affected — a critical piece of information for accurate diagnosis and treatment decisions.
GLS is performed alongside the heart triplex, with no additional preparation required. D. Boukis evaluates the findings within the overall clinical picture and issues a report with specific, individualised recommendations.
When is GLS needed?
Cardiotoxicity
Early detection from chemotherapy
Heart Failure
Patient monitoring
Subclinical Dysfunction
Detection before symptoms
Risk Stratification
In heart diseases
Athletes
High performance check
Therapy Follow-up
Effectiveness monitoring
GLS in Cardio-Oncology
GLS is the gold standard for early detection of cardiotoxicity from chemotherapy
Early Detection
Detects myocardial damage before ejection fraction reduction
Therapy Guidance
Allows timely adjustment or discontinuation of chemotherapy
Improved Prognosis
Prevention of irreversible cardiac damage
How is GLS performed?
GLS is performed during classic heart triplex with special GE Vivid E95 analysis software that measures microscopic deformation of myocardial fibers.
- Images are taken from all views
- Software analyzes deformation automatically
- Average GLS index is calculated
Duration
5-10 minutes additional to triplex
